What Goal should Rhodopsin Research Achieve?

What should we hope to achieve when treating rheumatoid arthritis?

Large multicenter trials: what do they achieve and what should be done in perfusion?

There have been a vast number of publications in the perfusion and cardiac surgical literature suggesting possible therapeutic benefits from many perfusion interventions. Most of the reports are case series and other observational studies; few are randomized trials, and most of these are small, focusing on surrogate endpoints. We know there are many factors that can affect outcome after cardiac...

What does randomisation achieve?

What are the benefi ts of random allocation in clinical studies? John Worrall, a philosopher of science, recently questioned whether evidence-based medicine’s advice to base therapeutic decisions on the results of randomised controlled trials (RCTs) could be justifi ed.1 2 Here we provide a response to Worrall and others who challenge the epistemological value of RCTs. Worrall’s primary target ...

I-14: Assisted Reproduction and Religion What Consideration Should Be and Should Not Be Relevant,

Several important issues are pertinent to an ethical discussion of the new technology today grouped under the name Assisted Reproduction Technology (ART). This is a moral imperative because each of us must decide what is to be considered ethically acceptable in assisted reproduction. Reflecting on the ethical dimension of ‘creating’ a new human life can play a major role in ensuring that in eac...

What every pediatrician should know about liver transplantation

Liver transplantation is the treatment of choice for children with end-stage liver disease.  Improvement in outcomes (allograft and patient survival) has led to widespread use of pediatric LT worldwide. This success is due to improvement in patient selection, transplant surgery, anesthesia/postoperative care and immunosuppression management. This review will focus on different aspects of LT whi...